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KMID : 0357920060400000190
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Korean Journal of Pathology
2006 Volume.40 No. 0 p.190 ~ p.190
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Melanotic Neuroectodermal Tumor of Infancy Occurring in the Femur
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Kim JH
Han CW/Choi YD/Lee JS/Lee MC/Lee JH
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Abstract
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Melanotic neuroectodermal tumor of infancy (MNTI) which was first described by Krompecher is a rare neoplasm. The vast majority develop within the first year of life and it is currently thought to be a neoplasm of neural crest derivation. The clinical course is generally benign. But the local recurrence rate is generally 15-20%, and metastases have been documented in a few cases. MNTI arises in the head and neck in 91.8%, mainly in the maxilla (68.6%). But other sites, such as the epididymis, mediastinum, shoulder, and uterus may rarely be involved. And only one case of MNTI was reported in a long bone such as femur by Johnson. We report a case of MNTI together with a review of literature, which occurred in the femur of a five-month-old boy.
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